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Male Infertility Drugs

Male infertility is diagnosed by a specialist urologist after a blood or semen sample analysis. The majority of cases relate to poor semen quality. Only about 5 percent of infertile men suffer from a hormonal imbalance, and only hormonal imbalances can be corrected with medication. Some drugs prescribed for such conditions are:

Gonadotropins: Gonadoptrins are usually prescribed for men with unexplained infertility; an exceptionally low sperm count, or less than 40 percent sperm motility. It is believed these aberrations are the results of disrupted signals between the pituitary gland, the hypothalamus and the testes that create a hormone imbalance. Usual gonadotropins prescribed are hCG and FSH, both of which are administered as injections.

Antiestrogen: Lack of gonadotropins is often caused because of testosterone deficiency.  Antiestrogen fertility drugs are often used to help stimulate the release of gonadotropins. The common forms of antiestrogen drugs prescribed are domiphene (Clomid), and tamoxifen (Novadex).

But sometimes the use of antiestorgens works the other way and boosts testosterone production to above normal levels and a degree where sperm production can be negatively impacted. It is necessary that men on antiestrogen therapy have their testosterone levels constantly monitored.

Bromocriptine: Fertility problems can also result from excess of prolactin in a man’s system which leads to a decrease in testosterone and abnormal sperm. Bromocriptine is prescribed to help decrease prolactin levels and correct sperm production.

Testosterone: Lack of testosterone is known as hypogonadism where synthetic testosterone is prescribed. The drug can be taken orally, or through injections or as a transdermal gel or patch.

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